Antiviral activity of 1,2,4-triazole derivatives (microreview)
نویسندگان
چکیده
منابع مشابه
Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives.
Seventy-six 2-phenylbenzimidazole derivatives were synthesized and evaluated in cell-based assays for cytotoxicity and antiviral activity against a panel of 10 RNA and DNA viruses. The most commonly affected viruses were, in decreasing order, CVB-2, BVDV, Sb-1, HSV-1, and YFV, while HIV-1 and VSV were not affected, and RSV, VV and Reo-1 were only susceptible to a few compounds. Thirty-nine comp...
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3,4-diaryl-1,2,4-triazole-5-yl-propenoic acid derivatives as cis or trans isomers were tested for their antimicrobial activity.
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Sodium 1-[4-amino-5-mercapto-4H-(1,2,4)triazol-3-yl]heptadecane-1-sulfonate 2 has been used as a new precursor to synthesize some important biologically active heterocycles. Reaction of 2 with carbon disulphide in pyridine and acid chlorides yields the 1,2,4-triazole derivatives 3, 4a and 4b. Condensation of 2 with appropriate aldehydes gives 5a-c which have been cyclized by treating with thiog...
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A series of cyclic analogues of bioactive thiosemicarbazide derivatives have been synthesized as potential antimycobacterial agents. The 4-amino-1,2,4-triazole-5-thione analogues (Ia-f) were prepared by heating a mixture of thiocarbohydrzide and appropriate carboxylic acids. Reaction of thiocarbohydrazide with γ-ketoesters in the presence of sodium methoxide furnished triazolopyridazine derivat...
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ژورنال
عنوان ژورنال: Chemistry of Heterocyclic Compounds
سال: 2021
ISSN: 0009-3122,1573-8353
DOI: 10.1007/s10593-021-02919-1